Dr. Wilmore Webley, PhD, presents
"Measles After 50 Years". Health
Watch USA(sm) 2025 Webinar: Combating Infectious Disease Challenges.
Aug. 29, 2025.
Wilmore Webley, PhD, Professor of Microbiology and Senior Vice Provost
for Equity and Inclusion at the University of Massachusetts, Amherst.
Dr. Webley discusses the research and vaccine history of the measles
virus, along with its severe clinical impact. He emphasizes that measles
causes not only acute illness but also “immune amnesia,” erasing immune
memory and leaving survivors vulnerable to other diseases. Due to the
virus's extreme contagiousness, a high rate of immunity in the
community, greater than 95%, is necessary for herd immunity to take
place and to stop the spread of the virus. As the presentation
discusses, the benefit of the vaccine greatly outweighs its risks.
Unfortunately, misinformation is rampant, and immunization rates are
falling. In many areas they are well below the level needed to achieve
herd immunity. Much of the misinformation can be traced back to a deeply
flawed 1998 study by Andrew Wakefield which was published in the Lancet
and later retracted by the Journal. The study was not controlled,
suboptimally conducted, and involved only 12 patients.(1) Numerous large
studies have not found a relationship between vaccines and autism. In
one study, unvaccinated individuals were even found to have a
statistically non-significant higher rate.(2,3) It is ironic that
hundreds of thousands of patients have been studied to counter the
initial 12-patient report. Research dollars could have been spent
elsewhere, such as researching other causes of autism. Health Watch
USA(sm) Conference, Aug. 29, 2025.
Key Points (AI Assisted):
• Measles is an ancient and highly contagious disease, originating
around 5,000 years ago, likely from a cattle virus, and has caused
significant mortality, particularly among Indigenous populations after
European colonization.
• Major scientific milestones include the isolation of the measles virus
in 1954, the first vaccine in 1963, and later understanding of
measles-induced “immune amnesia,” which erases immune memory and leaves
survivors susceptible to other diseases.
• Measles is extremely infectious: one person can spread it to 12–18
others. Herd immunity requires at least 95% vaccination coverage.
• Symptoms range from fever and rash to severe complications such as
pneumonia, encephalitis, and death. One in 1,000 children with measles
may die; other complications include ear infections and diarrhea.
• Vitamin A supplementation can reduce severe outcomes in malnourished
populations but does not prevent measles infection.
• The 1998 retracted study by Dr. Andrew Wakefield, et al, falsely
linked MMR vaccination to autism. Although now thoroughly discredited it
caused widespread vaccine hesitancy, leading to outbreaks and declining
vaccination rates.
• Numerous large-scale studies have found no connection between the MMR
vaccine and autism.
• Measles cases have surged in recent years, especially in communities
with low vaccination rates.
• Vaccination is highly effective: one dose offers about 95% protection;
two doses provide even greater immunity and help establish herd
immunity.
• Vaccine side effects are rare and mild compared to the risks of
measles and its complications.
• Dr. Webley stresses the importance of combating misinformation,
maintaining high vaccination coverage, and upholding evidence-based
science to protect public health.
References
(1) Godlee F, Smith J, Marcovitch H. Wakefield's article linking MMR
vaccine and autism was fraudulent. BMJ. 2011 Jan 5;342:c7452. doi:
10.1136/bmj.c7452. PMID: 21209060.
https://www.bmj.com/content/342/bmj.c7452.long
(2) Hviid A, Hansen JV, Frisch M, Melbye M. Measles, Mumps, Rubella
Vaccination and Autism: A Nationwide Cohort Study. Ann Intern Med. 2019
Apr 16;170(8):513-520. doi: 10.7326/M18-2101. Epub 2019 Mar 5. PMID:
30831578.
https://www.acpjournals.org/doi/10.7326/M18-2101
(3) Data on the MMR Vaccine & Autism | Visualized Health. Mar. 7, 2019.
https://www.clearvuehealth.com/b/autism-mmr-stats/
YouTube Video: https://youtu.be/a-ktPERtdWU
Health Watch USAsm Webinar, Combating Infectious Disease
Challenges. Have we gone twenty steps forward or backwards? Aug.
29, 2025
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